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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | K9 | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Victor Sanchez# | 9.77 | 1976-1981 | |
| 2 | Sandy Koufax* | 9.28 | 1955-1966 | |
| 3 | Marcos Ortega# | 8.85 | 1976-1981 | |
| 4 | J R Richard# | 8.83 | 1971-1981 | |
| 5 | Blake Green# | 8.80 | 1973-1981 | |
| 6 | Sam McDowell | 8.61 | 1961-1979 | |
| 7 | Nolan Ryan# | 8.50 | 1966-1981 | |
| 8 | Lowell Palmer | 8.28 | 1968-1979 | |
| 9 | Kenneth Kollmyer# | 8.20 | 1974-1981 | |
| 10 | Rafael Jimenez# | 8.02 | 1971-1981 | |
| 11 | Tom Hall# | 7.88 | 1968-1981 | |
| 12 | Tom M Carroll# | 7.87 | 1974-1981 | |
| 13 | Bob Veale | 7.79 | 1962-1974 | |
| 14 | Sam Jones | 7.64 | 1951-1964 | |
| 15 | Pete Richert | 7.62 | 1962-1975 | |
| 16 | Dick Stigman | 7.59 | 1958-1967 | |
| 17 | Marco Sarabia# | 7.52 | 1977-1981 | |
| 18 | Theodore Gilje | 7.51 | 1970-1980 | |
| 19 | Edwin Ramirez# | 7.49 | 1976-1981 | |
| 20 | Luis Tiant | 7.45 | 1964-1974 | |
| 21 | Mickey Lolich | 7.21 | 1963-1978 | |
| 22 | Dave Boswell | 7.16 | 1964-1975 | |
| 23 | Frank Tanana# | 7.06 | 1974-1981 | |
| 24 | Rube Waddell* | 7.04 | 1897-1910 | |
| 25 | Bob Gibson | 7.02 | 1959-1979 | |
| 26 | Vida Blue | 6.98 | 1969-1979 | |
| 27 | Buzz Capra# | 6.91 | 1971-1981 | |
| 27 | Juan Pizarro | 6.91 | 1957-1971 | |
| 29 | Ron Guidry# | 6.90 | 1972-1981 | |
| 30 | Jim Maloney | 6.89 | 1960-1974 | |
| 31 | Mario Soto# | 6.88 | 1977-1981 | |
| 32 | Rick Rhoden# | 6.87 | 1972-1981 | |
| 33 | Stan Williams | 6.83 | 1958-1974 | |
| 34 | Don McMahon | 6.80 | 1957-1971 | |
| 35 | Sammy Ellis | 6.79 | 1962-1969 | |
| 36 | Bobby Bolin | 6.76 | 1961-1974 | |
| 36 | Rudy May | 6.76 | 1965-1976 | |
| 38 | Jim Bunning | 6.74 | 1955-1973 | |
| 39 | Ray Culp | 6.65 | 1963-1979 | |
| 39 | Bob Turley | 6.65 | 1951-1963 | |
| 41 | John D'Acquisto# | 6.64 | 1972-1981 | |
| 42 | Denny Lemaster | 6.62 | 1962-1977 | |
| 42 | Frank Riccelli# | 6.62 | 1975-1981 | |
| 44 | Al Downing | 6.61 | 1961-1975 | |
| 45 | Bill Singer# | 6.60 | 1964-1981 | |
| 45 | Steve Carlton# | 6.60 | 1965-1981 | |
| 47 | Larry Yount# | 6.59 | 1970-1980 | |
| 48 | Bert Blyleven# | 6.53 | 1970-1981 | |
| 49 | Don Drysdale* | 6.52 | 1956-1969 | |
| 49 | Bob D Johnson | 6.52 | 1969-1978 | |
| 51 | Diego Segui | 6.51 | 1962-1971 | |
| 52 | Fergie Jenkins# | 6.50 | 1965-1981 | |
| 52 | Jim Lonborg | 6.50 | 1965-1973 | |
| 54 | Toad Ramsey | 6.49 | 1885-1890 | |
| 55 | Tom Seaver | 6.47 | 1967-1979 | |
| 56 | Sonny Siebert | 6.43 | 1964-1973 | |
| 57 | Steve Busby# | 6.39 | 1970-1981 | |
| 58 | Tom Phoebus | 6.36 | 1966-1976 | |
| 59 | Dennis Leonard# | 6.35 | 1971-1981 | |
| 59 | Tug McGraw# | 6.35 | 1965-1981 | |
| 59 | Chris Short | 6.35 | 1959-1974 | |
| 62 | Clay Kirby# | 6.34 | 1969-1981 | |
| 62 | Harvey Haddix | 6.34 | 1952-1965 | |
| 64 | Tom Griffin# | 6.32 | 1969-1981 | |
| 65 | Earl Wilson | 6.30 | 1959-1970 | |
| 65 | Dean Chance | 6.30 | 1961-1976 | |
| 67 | Dave Giusti | 6.23 | 1962-1975 | |
| 67 | Moe Drabowsky | 6.23 | 1956-1972 | |
| 69 | Dazzy Vance* | 6.20 | 1915-1935 | |
| 69 | Smoky Joe Wood | 6.20 | 1908-1920 | |
| 69 | Juan Marichal | 6.20 | 1960-1974 | |
| 72 | Stu Miller | 6.18 | 1952-1968 | |
| 73 | Don Sutton# | 6.15 | 1966-1981 | |
| 73 | Gary Peters | 6.15 | 1959-1975 | |
| 75 | Bill R Henry | 6.13 | 1952-1969 | |
| 76 | Jon Matlack# | 6.12 | 1971-1981 | |
| 76 | Barry Latman | 6.12 | 1957-1967 | |
| 78 | Gary Gentry# | 6.10 | 1969-1981 | |
| 78 | Rich Gossage | 6.10 | 1972-1979 | |
| 80 | Steve Brown# | 6.08 | 1975-1981 | |
| 81 | Al Worthington | 6.07 | 1953-1969 | |
| 81 | Grant Jackson | 6.07 | 1965-1978 | |
| 81 | Bob Feller* | 6.07 | 1936-1956 | |
| 84 | Andy Messersmith# | 6.06 | 1968-1981 | |
| 85 | Doug Rau# | 6.05 | 1970-1981 | |
| 86 | Ken Brett# | 6.02 | 1967-1980 | |
| 87 | Al Hrabosky# | 5.99 | 1971-1981 | |
| 87 | Ted W Abernathy | 5.99 | 1955-1973 | |
| 89 | Bob Locker | 5.98 | 1965-1978 | |
| 90 | Gary Nolan# | 5.97 | 1967-1981 | |
| 91 | Larry McWilliams# | 5.96 | 1974-1981 | |
| 91 | Luis Albo# | 5.96 | 1974-1981 | |
| 93 | Benjamin Ochoa# | 5.95 | 1974-1981 | |
| 94 | Dennis Bennett | 5.94 | 1962-1971 | |
| 94 | John Montefusco | 5.94 | 1973-1980 | |
| 96 | Randy Lerch# | 5.93 | 1976-1981 | |
| 97 | Joe Gibbon | 5.92 | 1960-1971 | |
| 98 | Steve D Barber | 5.91 | 1960-1970 | |
| 98 | Dave Kamhi# | 5.91 | 1975-1981 | |
| 98 | Don Wilson# | 5.91 | 1966-1981 |
