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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Eddie Mathews* | 493 | 1951-1968 | |
| 2 | Ron Santo | 381 | 1960-1977 | |
| 3 | Tony Perez | 265 | 1963-1980 | |
| 4 | Ken Boyer | 263 | 1955-1969 | |
| 5 | Jeff Burroughs# | 239 | 1970-1981 | |
| 6 | Mike Schmidt# | 235 | 1970-1981 | |
| 7 | Harmon Killebrew | 232 | 1954-1978 | |
| 7 | Brooks Robinson | 232 | 1955-1974 | |
| 9 | Sixto Lezcano# | 221 | 1971-1981 | |
| 10 | Ron Cey# | 220 | 1970-1981 | |
| 11 | Bill Melton# | 214 | 1968-1981 | |
| 12 | Al Rosen | 206 | 1947-1956 | |
| 13 | Sal Bando | 192 | 1966-1979 | |
| 14 | Willie Jones | 190 | 1947-1961 | |
| 15 | Harlond Clift | 178 | 1934-1945 | |
| 16 | Ken Keltner | 163 | 1937-1950 | |
| 17 | Clete Boyer | 158 | 1955-1973 | |
| 18 | Bob Elliott | 156 | 1939-1954 | |
| 19 | Graig Nettles | 153 | 1967-1977 | |
| 20 | Jim Ray Hart | 152 | 1963-1975 | |
| 21 | Richie Hebner# | 146 | 1968-1980 | |
| 22 | Pinky Higgins | 140 | 1930-1946 | |
| 23 | Eddie Yost | 139 | 1944-1962 | |
| 24 | George Brett# | 137 | 1970-1981 | |
| 25 | Bob Bailey# | 134 | 1962-1981 | |
| 26 | Frank Malzone | 133 | 1955-1966 | |
| 27 | Rennie Stennett# | 128 | 1970-1981 | |
| 28 | Ken McMullen | 116 | 1962-1976 | |
| 29 | Johnny Grubb# | 115 | 1971-1981 | |
| 30 | Bob Horner# | 114 | 1979-1981 | |
| 31 | Dick Allen | 112 | 1963-1978 | |
| 32 | Joe Foy | 109 | 1966-1978 | |
| 33 | Max Alvis | 108 | 1962-1969 | |
| 34 | Ryan MacFarland# | 107 | 1975-1981 | |
| 35 | Whitey Kurowski | 106 | 1941-1949 | |
| 35 | Marc Rhea# | 106 | 1971-1981 | |
| 37 | Jim Tabor | 104 | 1938-1951 | |
| 38 | Randy Jackson | 103 | 1950-1959 | |
| 38 | Hank Thompson | 103 | 1947-1956 | |
| 40 | Don Wert | 98 | 1963-1973 | |
| 41 | Frank Baker* | 96 | 1908-1922 | |
| 41 | Ray Jablonski | 96 | 1953-1960 | |
| 43 | Pinky Whitney | 92 | 1928-1939 | |
| 44 | Ray Boone | 91 | 1948-1960 | |
| 45 | Don Hoak | 89 | 1954-1964 | |
| 46 | Ed Charles | 86 | 1962-1969 | |
| 47 | Doug Rader | 76 | 1967-1976 | |
| 48 | Darrell Evans# | 75 | 1969-1981 | |
| 48 | Rich Rollins | 75 | 1961-1972 | |
| 48 | Joe Torre# | 75 | 1960-1981 | |
| 48 | Billy Werber | 75 | 1930-1942 | |
| 52 | Grady Hatton | 74 | 1946-1960 | |
| 53 | Jerry Denny | 73 | 1881-1894 | |
| 53 | George Kell | 73 | 1943-1957 | |
| 55 | Sid Gordon | 72 | 1941-1955 | |
| 55 | Frank J Thomas | 72 | 1951-1966 | |
| 57 | Freddie Lindstrom | 71 | 1924-1936 | |
| 58 | Pete Ward | 70 | 1962-1969 | |
| 59 | Aurelio Rodriguez# | 69 | 1967-1981 | |
| 59 | Red Rolfe | 69 | 1934-1942 | |
| 59 | Paul Schaal | 69 | 1964-1979 | |
| 59 | Charley Smith | 69 | 1960-1969 | |
| 63 | Hector Lopez | 66 | 1955-1966 | |
| 64 | Les Bell | 65 | 1923-1931 | |
| 64 | Jimmy Collins* | 65 | 1895-1908 | |
| 66 | Andy Carey | 64 | 1952-1962 | |
| 66 | Larry Parrish# | 64 | 1976-1981 | |
| 68 | Bill Nagel | 62 | 1939-1946 | |
| 69 | Billy Johnson | 61 | 1943-1953 | |
| 69 | Otto Velez# | 61 | 1970-1981 | |
| 71 | Barry Evans# | 60 | 1978-1981 | |
| 71 | Bill Joyce | 60 | 1890-1898 | |
| 71 | Denny Lyons | 60 | 1885-1897 | |
| 71 | Billy Nash | 60 | 1884-1898 | |
| 71 | Jaden Smith# | 60 | 1975-1981 | |
| 71 | Lou Whitaker# | 60 | 1975-1981 | |
| 77 | Kevin Bell# | 59 | 1978-1981 | |
| 77 | Frank Skaff | 59 | 1935-1946 | |
| 79 | Jose Perales# | 58 | 1979-1981 | |
| 79 | Bobby Thomson | 58 | 1946-1960 | |
| 79 | Pie Traynor* | 58 | 1920-1937 | |
| 82 | Stan Hack | 57 | 1932-1947 | |
| 82 | Bubba Phillips | 57 | 1955-1964 | |
| 84 | Carney Lansford# | 55 | 1977-1981 | |
| 84 | Al E Smith | 55 | 1950-1964 | |
| 86 | John Castino# | 54 | 1976-1981 | |
| 87 | Jimmy Dykes | 53 | 1918-1939 | |
| 88 | Hank Majeski | 52 | 1939-1955 | |
| 88 | Johnny Vergez | 52 | 1931-1936 | |
| 90 | Bob Aspromonte | 51 | 1956-1970 | |
| 90 | Marty McManus | 51 | 1920-1934 | |
| 92 | Billy Cox | 49 | 1941-1955 | |
| 92 | George C Scott | 49 | 1966-1978 | |
| 94 | Josh Grimes# | 45 | 1974-1981 | |
| 94 | Jeremy Nelson# | 45 | 1977-1981 | |
| 96 | Tommy Harper | 44 | 1962-1974 | |
| 97 | Gil McDougald | 43 | 1951-1960 | |
| 97 | Lew Riggs | 43 | 1934-1950 | |
| 97 | Heinie Zimmerman | 43 | 1907-1919 | |
| 100 | Ossie Bluege | 41 | 1922-1939 |
