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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | Gary Nolan# | 17 | 1967-1981 | |
| 2 | Tommy John# | 11 | 1963-1981 | |
| 3 | Bob Caruthers | 10 | 1884-1892 | |
| 3 | Dave McNally# | 10 | 1962-1981 | |
| 3 | Dick Ruthven# | 10 | 1972-1981 | |
| 6 | Bob Gibson | 9 | 1959-1979 | |
| 6 | Ed Halicki# | 9 | 1972-1981 | |
| 8 | Steve Carlton# | 8 | 1965-1981 | |
| 8 | Don Drysdale* | 8 | 1956-1969 | |
| 8 | Whitey Ford* | 8 | 1950-1967 | |
| 8 | Burleigh Grimes* | 8 | 1916-1934 | |
| 8 | Don Newcombe | 8 | 1949-1960 | |
| 8 | Allie Reynolds | 8 | 1942-1954 | |
| 8 | Charlie Root | 8 | 1923-1941 | |
| 15 | Burt Hooton | 7 | 1971-1978 | |
| 15 | Jim Palmer | 7 | 1965-1981 | |
| 15 | Frank Riccelli# | 7 | 1975-1981 | |
| 18 | Lew Burdette | 6 | 1950-1967 | |
| 18 | Steve Busby# | 6 | 1970-1981 | |
| 18 | Tom M Carroll# | 6 | 1974-1981 | |
| 18 | Roger Craig | 6 | 1955-1966 | |
| 18 | Chuck Dobson | 6 | 1966-1977 | |
| 18 | Sam McDowell | 6 | 1961-1979 | |
| 18 | Jim Merritt | 6 | 1965-1977 | |
| 18 | Bob Turley | 6 | 1951-1963 | |
| 18 | Tom Underwood# | 6 | 1974-1981 | |
| 27 | Jack Bentley | 5 | 1913-1927 | |
| 27 | Joe Black | 5 | 1952-1957 | |
| 27 | Dick Hughes | 5 | 1966-1968 | |
| 27 | Kenneth Kollmyer# | 5 | 1974-1981 | |
| 27 | Mickey Lolich | 5 | 1963-1978 | |
| 27 | Marcos Ortega# | 5 | 1976-1981 | |
| 27 | Vic Raschi | 5 | 1946-1955 | |
| 27 | Jerry Reuss# | 5 | 1969-1981 | |
| 27 | Tom Seaver | 5 | 1967-1979 | |
| 27 | Warren Spahn* | 5 | 1942-1965 | |
| 27 | Ralph Terry | 5 | 1956-1967 | |
| 27 | Junior Thompson | 5 | 1939-1949 | |
| 39 | Dick Bosman# | 4 | 1966-1981 | |
| 39 | Thomas Boyd# | 4 | 1975-1981 | |
| 39 | Nelson Briles | 4 | 1965-1974 | |
| 39 | Dizzy Dean* | 4 | 1930-1947 | |
| 39 | Larry Dierker# | 4 | 1964-1981 | |
| 39 | Bob Grim | 4 | 1954-1962 | |
| 39 | Willie Hernandez# | 4 | 1975-1981 | |
| 39 | Catfish Hunter# | 4 | 1965-1981 | |
| 39 | Pat Jarvis | 4 | 1966-1979 | |
| 39 | Bob D Johnson | 4 | 1969-1978 | |
| 39 | Walter Johnson* | 4 | 1907-1927 | |
| 39 | Clay Kirby# | 4 | 1969-1981 | |
| 39 | Billy Loes | 4 | 1950-1961 | |
| 39 | Sal Maglie | 4 | 1945-1958 | |
| 39 | Rube Marquard | 4 | 1908-1925 | |
| 39 | Joe Niekro | 4 | 1967-1977 | |
| 39 | Doug Rau# | 4 | 1970-1981 | |
| 39 | Preacher Roe | 4 | 1938-1954 | |
| 39 | Red Ruffing* | 4 | 1924-1947 | |
| 39 | Bill Sherdel | 4 | 1918-1932 | |
| 59 | Pete Alexander* | 3 | 1911-1930 | |
| 59 | Ken Brett# | 3 | 1967-1980 | |
| 59 | Steve Brown# | 3 | 1975-1981 | |
| 59 | Tommy Byrne | 3 | 1943-1957 | |
| 59 | Ice Box Chamberlin | 3 | 1886-1896 | |
| 59 | Mort Cooper | 3 | 1938-1949 | |
| 59 | Ed Crane | 3 | 1884-1893 | |
| 59 | Paul Derringer | 3 | 1931-1945 | |
| 59 | Al Downing | 3 | 1961-1975 | |
| 59 | Bob Feller* | 3 | 1936-1956 | |
| 59 | Blake Green# | 3 | 1973-1981 | |
| 59 | Jesse Haines | 3 | 1918-1937 | |
| 59 | Jim Hardin | 3 | 1967-1980 | |
| 59 | Carl Hubbell* | 3 | 1928-1943 | |
| 59 | Syl Johnson | 3 | 1922-1940 | |
| 59 | Randy Jones# | 3 | 1973-1981 | |
| 59 | Jerry Koosman | 3 | 1967-1981 | |
| 59 | Ray Kremer | 3 | 1924-1933 | |
| 59 | Clem Labine | 3 | 1950-1962 | |
| 59 | Don Larsen | 3 | 1953-1967 | |
| 59 | Vern Law | 3 | 1950-1967 | |
| 59 | Jim Lonborg | 3 | 1965-1973 | |
| 59 | Rudy May | 3 | 1965-1976 | |
| 59 | Denny McLain# | 3 | 1963-1981 | |
| 59 | Hugh McQuillan | 3 | 1918-1927 | |
| 59 | Blue Moon Odom | 3 | 1964-1979 | |
| 59 | Herb Pennock* | 3 | 1912-1934 | |
| 59 | Jim Perry | 3 | 1959-1974 | |
| 59 | Johnny Podres | 3 | 1953-1969 | |
| 59 | Flint Rhem | 3 | 1924-1936 | |
| 59 | Schoolboy Rowe | 3 | 1933-1950 | |
| 59 | Nolan Ryan# | 3 | 1966-1981 | |
| 59 | Hal Schumacher | 3 | 1931-1946 | |
| 59 | Bob Shaw | 3 | 1957-1967 | |
| 59 | Sonny Siebert | 3 | 1964-1973 | |
| 59 | Don Sutton# | 3 | 1966-1981 | |
| 95 | Cy Acosta | 2 | 1971-1976 | |
| 95 | Babe Adams | 2 | 1906-1926 | |
| 95 | Vic Aldridge | 2 | 1917-1928 | |
| 95 | Jesse Barnes | 2 | 1915-1927 | |
| 95 | Virgil Barnes | 2 | 1919-1928 | |
| 95 | Johnny Beazley | 2 | 1941-1949 |
