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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | TB | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Lou Gehrig* | 447 | 1927 | |
| 2 | Jimmie Foxx* | 438 | 1932 | |
| 3 | Lou Gehrig* | 419 | 1930 | |
| 4 | Lou Gehrig* | 410 | 1931 | |
| 5 | Lou Gehrig* | 409 | 1934 | |
| 6 | Hal Trosky Sr | 405 | 1936 | |
| 7 | Jimmie Foxx* | 403 | 1933 | |
| 7 | Lou Gehrig* | 403 | 1936 | |
| 9 | George Sisler* | 399 | 1920 | |
| 10 | Jimmie Foxx* | 398 | 1938 | |
| 11 | Hank Greenberg* | 397 | 1937 | |
| 12 | Bill Terry* | 392 | 1930 | |
| 13 | Hank Greenberg* | 389 | 1935 | |
| 14 | Hank Greenberg* | 380 | 1938 | |
| 15 | Hal Trosky Sr | 374 | 1934 | |
| 16 | Bill Terry* | 373 | 1932 | |
| 17 | Lou Gehrig* | 370 | 1932 | |
| 18 | Jimmie Foxx* | 369 | 1936 | |
| 18 | Ripper Collins | 369 | 1934 | |
| 20 | Ted Kluszewski | 368 | 1954 | |
| 20 | Johnny Mize* | 368 | 1940 | |
| 22 | Stan Musial* | 366 | 1946 | |
| 22 | Lou Gehrig* | 366 | 1937 | |
| 24 | Lou Gehrig* | 364 | 1928 | |
| 25 | Dale Alexander | 363 | 1929 | |
| 26 | Jim Bottomley | 362 | 1928 | |
| 27 | Johnny Mize* | 360 | 1947 | |
| 28 | Lou Gehrig* | 359 | 1933 | |
| 29 | Ted Kluszewski | 358 | 1955 | |
| 29 | Jimmie Foxx* | 358 | 1930 | |
| 29 | Jim Bottomley | 358 | 1925 | |
| 32 | Hank Greenberg* | 356 | 1934 | |
| 32 | Orlando Cepeda | 356 | 1961 | |
| 34 | Felipe Alou | 355 | 1966 | |
| 35 | Norm Cash | 354 | 1961 | |
| 36 | Johnny Mize* | 353 | 1939 | |
| 37 | Jimmie Foxx* | 352 | 1934 | |
| 38 | Ed Morgan | 351 | 1930 | |
| 39 | George Sisler* | 348 | 1922 | |
| 40 | Dick Allen | 343 | 1973 | |
| 40 | Rudy York | 343 | 1940 | |
| 42 | Jason D Thompson# | 342 | 1979 | |
| 43 | Jimmie Foxx* | 340 | 1935 | |
| 44 | Gil Hodges | 335 | 1954 | |
| 45 | Jason D Thompson# | 334 | 1978 | |
| 46 | Johnny Mize* | 333 | 1937 | |
| 47 | Stan Musial* | 331 | 1950 | |
| 48 | Hal Trosky Sr | 329 | 1937 | |
| 49 | Harmon Killebrew | 328 | 1961 | |
| 50 | Eddie Robinson | 327 | 1946 | |
| 50 | Lee May | 327 | 1965 | |
| 52 | Walt Dropo | 326 | 1950 | |
| 52 | George Sisler* | 326 | 1921 | |
| 52 | Orlando Cepeda | 326 | 1963 | |
| 52 | Johnny Mize* | 326 | 1938 | |
| 56 | Ted Kluszewski | 325 | 1953 | |
| 57 | Jimmie Foxx* | 324 | 1939 | |
| 57 | Orlando Cepeda | 324 | 1962 | |
| 59 | Lee May | 323 | 1974 | |
| 59 | Bill Terry* | 323 | 1931 | |
| 59 | Bill D White | 323 | 1963 | |
| 59 | Jimmie Foxx* | 323 | 1929 | |
| 59 | Lou Gehrig* | 323 | 1929 | |
| 64 | Willie McCovey | 322 | 1969 | |
| 64 | Orlando Cepeda | 322 | 1970 | |
| 66 | Lee May | 321 | 1969 | |
| 67 | Dick Stuart | 319 | 1963 | |
| 67 | Del Bissonette | 319 | 1928 | |
| 69 | Jim Bottomley | 318 | 1929 | |
| 69 | George McQuinn | 318 | 1939 | |
| 69 | Stan Musial* | 318 | 1955 | |
| 72 | Bill Terry* | 317 | 1929 | |
| 72 | Don Hurst | 317 | 1932 | |
| 74 | Orlando Cepeda | 316 | 1959 | |
| 74 | George Crowe | 316 | 1951 | |
| 74 | Lee May | 316 | 1970 | |
| 74 | Hank Greenberg* | 316 | 1946 | |
| 74 | Johnny Mize* | 316 | 1948 | |
| 79 | Frank Robinson | 315 | 1959 | |
| 79 | Mickey Vernon | 315 | 1953 | |
| 81 | Lou Gehrig* | 314 | 1926 | |
| 81 | Jim Gentile | 314 | 1961 | |
| 83 | Frank McCormick | 312 | 1939 | |
| 83 | Lou Gehrig* | 312 | 1935 | |
| 85 | George Sisler* | 311 | 1925 | |
| 85 | Tom Alston | 311 | 1953 | |
| 85 | Hank Greenberg* | 311 | 1939 | |
| 88 | Stan Musial* | 310 | 1956 | |
| 88 | High Pockets Kelly | 310 | 1921 | |
| 88 | Jack Fournier | 310 | 1925 | |
| 88 | Nap Lajoie* | 310 | 1897 | |
| 92 | Dick Stuart | 309 | 1961 | |
| 92 | Don Hurst | 309 | 1929 | |
| 92 | Orlando Cepeda | 309 | 1958 | |
| 92 | Lee May | 309 | 1973 | |
| 96 | Steve Garvey# | 308 | 1978 | |
| 97 | Ernie Banks* | 307 | 1962 | |
| 97 | Stan Musial* | 307 | 1957 | |
| 97 | Gil Hodges | 307 | 1951 | |
| 97 | Randy Edwards# | 307 | 1979 |
